Although not all of these side effects may occur, if they do occur they may need medical attention. You may report side effects to the FDA at 1-800-FDA-1088. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Side effects What side effects can occur from Nitazoxanide? If you have any unusual effects, contact your doctor or pharmacist promptly. It is poorly soluble in ethanol and practically insoluble in water. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 500 mg Nitazoxanide taken orally every 12 hours with food for 3 days. Trouble Breathing. Pharmacology Pharmacodynamics. Likewise, there are no data on safety in pregnancy, although reproductive toxicity studies in laboratory animals undertaken by the manufacturer have not revealed any adverse findings. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Adverse events occurring in <1% of more than 2000 HIV-uninfected patients participating in clinical trials included anorexia, flatulence, increased appetite, enlarged salivary glands, fever, infection, malaise, elevated creatinine levels, elevated levels of alanine a… However, many people have no side effects or only have minor side effects. Nitazoxanide side effects Central Nervous System- Headache. Side effects were generally mild. redness of the skin. Portions of this document last updated: Feb. 01, 2020. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There is no information about the presence of nitazoxanide in human milk, the effects on the breast-fed infant, or the effects on milk production. Melbourne: Therapeutic Guidelines Limited "eTG complete [Online] Available from: URL: http://online.tg.org.au/complete/desktop/tgc.htm." 1. Gastroesophageal Reflux Disease. Change in color of urine. Wash your hands, scrub your fingernails and shower often. Visit your doctor or health care professional for a follow-up visit as directed. Nitazoxanide belongs to a group of drugs called antiprotozoal agents. Call your doctor for medical advice about side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. ALINIA Tablets and ALINIA for Oral Suspension contain the active ingredient, nitazoxanide, a synthetic antiprotozoal for oral administration. Adverse events have been mild and transient and principally related to the gastrointestinal tract, such as abdominal pain, diarrhea, and nausea. Romark Laboratories L.C., Tampa, FL. discolored urine. Medically reviewed by Drugs.com. 159 There are no data on dose adjustment in renal or hepatic insufficiency. pregnancy, upcoming surgery, etc. Applies to nitazoxanide: oral powder for suspension, oral tablet. Fox LM, Saravolatz LD "Nitazoxanide: a new thiazolide antiparasitic agent." If you notice any other effects, check with your healthcare professional. Nitazoxanide may cause side effects. Along with its needed effects, a medicine may cause some unwanted effects. Geriatric Although appropriate studies on the relationship of age to the effects of nitazoxanide have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of nitazoxanide in the elderly. Other, less serious side effects may be more likely to occur. "Product Information. Nitazoxanide side effects. Chen L, Xiong J, Bao L, Shi Y. Convalescent plasma as a potential therapy for COVID-19. Nitazoxanide Use as Part of an Empiric Multi-Drug Regimen in Treating Children with Suspected Helicobacter pylori Infection May 2015 Case Reports in Gastroenterology 9(1):36-42 A Skin Rash. dazole and nitazoxanide ex ert essentially differential effects on G. duoden alis tr ophozoites in vitro, with respect to morpho- logical and ultr astructural alter ations, also suggesting that the Stomach pain. This content does not have an Arabic version. Mayo Clinic does not endorse companies or products. Other side effects not listed may also occur in some patients. Int J Clin Pharmacol Ther 40 (2002): 221-7, 4. Nitazoxanide Side Effects. to 4 g with minimal gastrointestinal side effects. At present, there are no documented drug-drug interactions. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. Nitazoxanide is well tolerated when administered in the recommended dose, with reported side effects being no different than placebo. Last updated on Apr 8, 2020. Stockis A, De Bruyn S, Gengler C, Rosillon D "Nitazoxanide pharmacokinetics and tolerability in man during 7 days dosing with 0.5 g and 1 g b.i.d." vitamins, herbal supplements, etc. Incidence not known. The side effects of nitazoxanide do not significantly differ from a placebo treatment for giardiasis; these symptoms include stomach pain, headache, upset stomach, vomiting, discolored urine, excessive urinating, skin rash, itching, fever, flu syndrome, and others. Tizoxanide (the active metabolite of nitazoxanide) is highly bound to plasma protein (>99.9%). ).Some health conditions may make you more susceptible to the side-effects of the drug. Although not all of these side effects may occur, if they do occur they may need medical attention. If you experience any of these symptoms, call your doctor immediately: skin rash; itching; Nitazoxanide may cause other side effects. However, safety and efficacy of nitazoxanide oral suspension has not been established in children younger than 1 year of age. Nitazoxanide - Indications, Dosage, Side Effects and Precautions General Brands Prescription Contraindications Side effects Dosage How to Take Warning Storage Medindia Nizonide 500 Tablet is used for the treatment of diarrhea in patients with protozoal infections caused by the protozoa Giardia and Cryptosporidium. This drug usually has no side effects. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. This site complies with the HONcode standard for trustworthy health information: verify here. These side effects may go away during treatment as your body adjusts to the medicine. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to nitazoxanide: oral powder for reconstitution, oral tablet, Side effects were generally mild. Lancet Infect Dis. You may need to have tests done to check that the infection is cleared. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 25. Read the entire detailed patient monograph for Alinia (Nitazoxanide) Check with your doctor immediately if any of the following side effects occur while taking nitazoxanide: Some side effects of nitazoxanide may occur that usually do not need medical attention. This content does not have an English version. The most common adverse reactions in ≥2% of patients were abdominal pain, headache, chromaturia and nausea. 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